- From
- Pakistan
- Hospital for treatment
- Jiahui International Hospital, Shanghai
- Disease
- Relapsed and refractory diffuse large B-cell lymphoma
- Treatment/medical stage
- CAR-T cell therapy and multidisciplinary support
Previous treatments failed to continuously control the disease
Muhammad, who is from Quetta, Pakistan, was diagnosed with diffuse large B-cell lymphoma in 2021. After multiple rounds of chemotherapy, he received a bone marrow transplant in 2024, only to relapse about 20 days later. The patient and his family contacted hospitals in multiple countries to explore the possibility of further treatment.
Promote communication into a specific diagnosis and treatment plan
The Jiahui team responded to the condition and proposed preliminary arrangements in the early communication. In early 2026, Muhammad came to Shanghai. On admission, the disease had already affected the lungs, pleura, and bones, and was accompanied by significant pain, fever, and weight loss; the medical team initiated treatment preparations after evaluation.
Support during treatment and hospitalization
In early April, he completed T cell collection and subsequently received bridging therapy, lymphocytic preconditioning and CAR-T infusion. During his hospitalization, the hospital assisted with Urdu communication through translation and written instructions, and also took care of his halal dietary needs, making daily communication during complex treatments smoother.
Examination changes and follow-up
PET-CT in early May showed that the lymph node lesions had shrunk, the lactate dehydrogenase index returned to normal, and the pain was also relieved. He returned to Pakistan on May 8 and the team arranged for a follow-up review. The reports documented early treatment responses and did not describe them as final cures.
Report source
Jiahui International Cancer Center · 2026-05-28 · View the original report ↗
- 来自
- 巴基斯坦
- 就诊医院
- 上海嘉会国际医院
- 疾病
- 复发难治性弥漫大 B 细胞淋巴瘤
- 治疗／就医阶段
- CAR-T 细胞治疗与多学科支持
既往治疗未能持续控制疾病
来自巴基斯坦奎达的 Muhammad 于 2021 年被诊断为弥漫大 B 细胞淋巴瘤。多次化疗后，他在 2024 年接受骨髓移植，却在约 20 天后再次复发。患者与家人联系多个国家的医院，寻找进一步治疗的可能性。
把沟通推进为具体诊疗计划
嘉会团队在前期沟通中回应病情并提出初步安排。2026 年初，Muhammad 来到上海。入院时疾病已累及肺、胸膜和骨骼，伴有明显疼痛、发热和体重下降；医疗团队评估后启动治疗准备。
治疗与住院期间的支持
4 月初，他完成 T 细胞采集，随后接受桥接治疗、清淋预处理及 CAR-T 回输。住院期间，院方通过翻译及书面说明协助乌尔都语沟通，也照顾其清真饮食需求，让复杂治疗中的日常沟通更加顺畅。
检查变化与后续随访
5 月初的 PET-CT 显示淋巴结病灶缩小，乳酸脱氢酶指标恢复正常，疼痛也有所减轻。5 月 8 日，他返回巴基斯坦，团队安排后续复查。报道记录的是早期治疗反应，没有将其表述为最终治愈。